Hydrodynamics of a pilot-scale in-line high shear mixer (HSM) with double rows of ultrafine rotor and stator teeth, including the velocity profiles and power consumptions, were measured using laser Doppler anemometry and a torque transducer, respectively. Computational fluid dynamics simulations were conducted using the standard k-ε turbulence model with first- and second-order accuracy and large eddy simulation (LES) with the standard Smagorinsky–Lilly subgrid scale model. Predictive capabilities of the different turbulence models and discretization schemes were assessed based on the experimental data. It is found that the current LES can predict accurately the flow patterns for the strongly rotating and locally anisotropic turbulent flows in the complex in-line HSM. The results obtained are fundamental to explore potential applications of the in-line teethed HSMs to intensify chemical reaction processes. © 2013 American Institute of Chemical Engineers AIChE J, 60: 1143–1155, 2014
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