Perturbation velocities in gas-liquid partition chromatographic columns

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Abstract

The characteristic velocities in binary and particular ternary cases allow straightforward calculation of equilibrium partition coefficients for components present in both flowing and fixed phases. It is shown in the case of a general N-component flowing phase that N-1 characteristic velocities arise. In theory N-1 equilibrium partition coefficients can be obtained from measurements of these velocities. It is also shown that radioactive tagging of one component provides a distinct characteristic velocity, which can be used either to obtain the Nth equilibrium coefficient or to eliminate a parameter which is especially subject to experimental error.

The analytically determined characteristic velocities are compared with pulse velocities obtained from numerical solution of the original balance equations. The agreement over a range of solute concentrations is excellent.

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