This investigation was supported by PHS grant DE 01971–02.
Bone formation and resorption around developing teeth transplanted into the femur
Article first published online: 3 FEB 2005
Copyright © 1966 Wiley-Liss, Inc.
American Journal of Anatomy
Volume 118, Issue 1, pages 91–102, January 1966
How to Cite
Hoffman, R. L. (1966), Bone formation and resorption around developing teeth transplanted into the femur. Am. J. Anat., 118: 91–102. doi: 10.1002/aja.1001180106
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
Seven of 24 newborn hamsters developing maxillary molars which were transplanted to the femur for 28 days showed growth and development of crowns and roots. Enamel, dentin, pulp, cementum, periodontal ligament and alveolar bone proper developed in their normal locations just as they had done previously in molars transplanted into subcutaneous connective tissues. Several relationships were observed between alveolar bone proper, developed in the foreign body environment and under the inductive influence of the tooth root, and femoral bone. Femoral bone was continuous with alvolar bone and supported the tooth socket. In some areas near transplanted molar roots, femoral bone was built out to join and support alveolar bone. In other areas, femoral bone was resorbed by the development of a molar root or the molar root was diverted from its normal direction of development. Despite the effort to orient transplanted molars for eruption, the orientation was altered and no evidence for tooth eruption was observed.