Recipient of Summer Medical Research Fellowship.
Projections of adrenocortical cells into sinusoidal lumina. Influence of prostaglandin E1†
Article first published online: 3 FEB 2005
Copyright © 1972 Wiley-Liss, Inc.
American Journal of Anatomy
Volume 135, Issue 1, pages 135–140, September 1972
How to Cite
Penney, D. P., Averill, K. and Olson, J. (1972), Projections of adrenocortical cells into sinusoidal lumina. Influence of prostaglandin E1. Am. J. Anat., 135: 135–140. doi: 10.1002/aja.1001350111
Supported by U.S.P.H.S. Grant AM-09561.
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
Cytoplasmic projections of adrenocortical cells have been observed within sinusoidal lumina of various species. The projections contain organelles and inclusions which are morphologically identical to those in subjacent functional cortical cells, and appear to be capable of hormone biosynthesis. The frequency with which the projections are observed is markedly enhanced by the administration of prostaglandin E1. Continuity has been observed between the projections and the parenchymal cells. Whether or not these morphological entities reflect a mechanism for an enhanced response to corticotropin stimulation remains uncertain. Their association with cellular autolysis or degradation appears doubtful.