Neuropeptides in sensory perikarya projecting to the rat ovary
Article first published online: 3 FEB 2005
Copyright © 1987 Wiley-Liss, Inc.
American Journal of Anatomy
Volume 179, Issue 3, pages 269–276, July 1987
How to Cite
McNeill, D. L. and Burden, H. W. (1987), Neuropeptides in sensory perikarya projecting to the rat ovary. Am. J. Anat., 179: 269–276. doi: 10.1002/aja.1001790308
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
- Manuscript Accepted: 14 JUL 1986
- Manuscript Received: 14 APR 1986
Afferent perikarya in dorsal root ganglia (DRG) at the T13 and L1 segmental levels projecting to the rat ovary were identified by utilizing the fluorescent retrograde tracer true blue (TB). Subsequently, TB-labeled ovarian afferent perikarya in DRG were examined for vasoactive intestinal polypeptide (VIP), substance P (SP), cholecystokinin-8 (CCK-8), neuropeptide Y (NPY), and somatostatin (SOM) immunoreactivity and for the presence of fluoride-resistant acid phosphatase (FRAP) enzyme activity. Of the ovarian afferent perikarya at the T13 and L1 segmental levels, 20.5% displayed VIP immunoreactivity, 23.8% displayed SP immunoreactivity, and 43.1% were immunoreactive for CCK-8. No ovarian afferent perikarya contained SOM or NYP immunoreactivity or FRAP activity. It is suggested that different neuropeptides may participate in modulation of specific ovarian functions.