Hematologic reference values for African American children and adolescents
Article first published online: 18 DEC 2006
Copyright © 2006 Wiley-Liss, Inc.
American Journal of Hematology
Volume 82, Issue 7, pages 611–614, July 2007
How to Cite
Robins, E. B. and Blum, S. (2007), Hematologic reference values for African American children and adolescents. Am. J. Hematol., 82: 611–614. doi: 10.1002/ajh.20848
- Issue published online: 8 JUN 2007
- Article first published online: 18 DEC 2006
- Manuscript Accepted: 16 OCT 2006
- Manuscript Revised: 27 SEP 2006
- Manuscript Received: 19 JUN 2006
- African American
Anemia is prevalent among African American children. When evaluating pediatric patients for anemia, clinicians refer to the normative hematological reference values in reference textbooks. These reference values are used in spite of evidence that healthy African American people of all ages have average hemoglobin concentrations from 0.5 to 0.73 g/dl below those of Whites. In an earlier study, using samples from 2,161 healthy African American children from 2 to 18 years old, we found a statistically significant difference (P < 0.0001) in the mean hemoglobin value for each age group as compared to reference normative mean hemoglobin values. Here we present the results of a comparative analysis of the data set from our previous study and the data set from the National Health and Nutrition Examination Surveys III (NHANES III) 1988–1994. We found no statistically significant difference between these data sets with respect to the hemoglobin values for any age or sex group, confirming that African American children and adolescents have lower mean hemoglobin values than do Whites. Use of the reference hemoglobin values presented here will help prevent the misdiagnosis of anemia in African American children and thereby minimize unnecessary hematological workups and treatment. Am. J. Hematol. 82: 2007. © 2006 Wiley-Liss, Inc.