Cold agglutinin induced autoimmune hemolytic anemia and NK-cell leukemia—A new association

Authors

  • Amy Skorupa,

    1. Department of Medicine, Division of Hematology/Oncology, Medical University of South Carolina, Charleston, South Carolina
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  • Uzair B. Chaudhary,

    1. Department of Medicine, Division of Hematology/Oncology, Medical University of South Carolina, Charleston, South Carolina
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  • John Lazarchick

    Corresponding author
    1. Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina
    • Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 165 Ashley Avenue, PO Box 250908, Charleston, SC 29425
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Abstract

Cold agglutinin induced autoimmune hemolytic anemia is uncommonly associated with leukemia and lymphomas. We present a case of a young Mexican female presenting with a cold agglutinin hemolytic anemia with expression of a rare Pr antigen specificity and an aggressive NK-cell leukemia. Our patient had a rapid fatal course. To our knowledge this is the first reported case of such an association. Am. J. Hematol., 2007. © 2007 Wiley-Liss, Inc.

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