Androgens and energy allocation: Quasi-experimental evidence for effects of influenza vaccination on men's testosterone
Article first published online: 22 OCT 2008
Copyright © 2008 Wiley-Liss, Inc.
American Journal of Human Biology
Volume 21, Issue 1, pages 133–135, January 2009
How to Cite
Simmons, Z. L. and Roney, J. R. (2009), Androgens and energy allocation: Quasi-experimental evidence for effects of influenza vaccination on men's testosterone. Am. J. Hum. Biol., 21: 133–135. doi: 10.1002/ajhb.20837
- Issue published online: 5 DEC 2008
- Article first published online: 22 OCT 2008
- Manuscript Accepted: 9 SEP 2008
- Manuscript Revised: 4 SEP 2008
- Manuscript Received: 18 JUL 2008
Androgens are proposed to allocate finite energetic resources away from immune function and toward anabolic processes related to reproductive effort. In situations of pathogen exposure, the significant energetic demands associated with mounting an immune response are expected to produce a decrease in androgen levels and commensurate redistribution of energy. We tested the hypothesis that even the mild immune challenge associated with vaccination may cause a decline in men's testosterone. As predicted, men who received an influenza vaccination exhibited a more negative change in testosterone over a 2-week period than did men in a nonequivalent control group who were not vaccinated. These results suggest that men's androgen concentrations may be finely calibrated to trade-offs between the energetic demands of immune responses and other life history problems. Am. J. Hum. Biol., 2009. © 2008 Wiley-Liss, Inc.