This article is a US Government work and, as such, is in the public domain in the United States of America.
Pearl Memorial Lecture/Special Section: 2008 Plenary Session Advances in Evolutionary Endocrinology
The gestational timing of pregnancy loss: Adaptive strategy?†
Article first published online: 30 APR 2009
Copyright © 2009 Wiley-Liss, Inc.
American Journal of Human Biology
Volume 21, Issue 6, pages 725–727, November/December 2009
How to Cite
Baird, D. D. (2009), The gestational timing of pregnancy loss: Adaptive strategy?. Am. J. Hum. Biol., 21: 725–727. doi: 10.1002/ajhb.20935
- Issue published online: 9 OCT 2009
- Article first published online: 30 APR 2009
- Manuscript Accepted: 2 MAR 2009
- Manuscript Received: 26 FEB 2009
- NIEHS, NIH (Intramural Research Program).
This commentary links early pregnancy milestones (rescue of the corpus luteum, the luteal-placental shift, and blocking of the spiral arteries) with the pattern of gestation-specific pregnancy loss in humans. The objective is to describe the pattern and present an adaptive hypothesis: that high first trimester pregnancy loss results from selection to reduce the risk of maternal morbidity and mortality associated with human delivery. Specific questions within the broad framework of this hypothesis can be addressed with research in comparative physiology and endocrinology. Am. J. Hum. Biol., 2009. Published 2009 Wiley-Liss, Inc.