Estimates of interethnic admixture in the Brazilian population using a panel of 24 X-linked insertion/deletion markers
Article first published online: 23 SEP 2010
Copyright © 2010 Wiley-Liss, Inc.
American Journal of Human Biology
Volume 22, Issue 6, pages 849–852, November/December 2010
How to Cite
Resque, R. L., Freitas, N. D. S. D. C., Rodrigues, E. M. R., Guerreiro, J. F., Santos, N. P. C. D., Ribeiro Dos Santos, Â., Zago, M. A. and Santos, S. (2010), Estimates of interethnic admixture in the Brazilian population using a panel of 24 X-linked insertion/deletion markers. Am. J. Hum. Biol., 22: 849–852. doi: 10.1002/ajhb.21089
- Issue published online: 16 OCT 2010
- Article first published online: 23 SEP 2010
- Manuscript Accepted: 18 JUL 2010
- Manuscript Revised: 8 JUL 2010
- Manuscript Received: 3 MAR 2010
- Universidade Federal do Para (UFPA)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico(CNPq)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
- Financiadora de Estudos e Projetos (FINEP)
Objectives. In this study, we aimed to identify ancestry informative haplotypes and make interethnic admixture estimates using X-chromosome markers.
Methods. A significant sample (461 individuals) of European, African, and Native American populations was analyzed, and four linkage groups were identified. The data obtained were used to describe the ancestral contribution of populations from four different geographical regions of Brazil (745 individuals).
Results. The global interethnic admixture estimates of the four mixed populations under investigation were calculated applying all the 24 insertion/deletion (INDEL) markers. In the North region, a larger Native Americans ancestry was observed (42%). The Northeast and Southeast regions had smaller Native American contribution (27% in both of them). In the South region, there was a large European contribution (46%).
Conclusions. The estimates obtained are compatible with expectations for a colonization model with biased admixture between European men (one X chromosome) and Native American and African women (two X chromosomes), so the 24 X-INDEL panel described here can be a useful to make admixture interethnic estimates in Brazilian populations. Am. J. Hum. Biol., 2010. © 2010 Wiley-Liss, Inc.