Child patterns of growth delay and cognitive development in a bolivian mining city
Article first published online: 7 NOV 2012
Copyright © 2012 Wiley Periodicals, Inc.
American Journal of Human Biology
Volume 25, Issue 1, pages 94–100, January/February 2013
How to Cite
Ruiz-Castell, M., Carsin, A.-E., Barbieri, F.-L., Paco, P., Gardon, J. and Sunyer, J. (2013), Child patterns of growth delay and cognitive development in a bolivian mining city. Am. J. Hum. Biol., 25: 94–100. doi: 10.1002/ajhb.22346
- Issue published online: 18 DEC 2012
- Article first published online: 7 NOV 2012
- Manuscript Accepted: 10 OCT 2012
- Manuscript Revised: 28 SEP 2012
- Manuscript Received: 22 MAY 2012
- Agence Nationale de la Recherche (ANR) in cooperation with the SELADIS Institute
- Universidad Mayor de San Andrés, Bolivia
- Institut de Recherche pour le Développement (IRD)
- Municipal Institute of Medical Research (IMIM-Hospital del Mar)
- Centre for Research in Environmental Epidemiology (CREAL)
This study aims to (1) follow up and characterize infant growth patterns during the first year of life in Bolivia, and (2) determine whether there exists an association between weight gain and cognitive development in children living near contaminated mining industries.
Data on 175 children participating to the ToxBol (Toxicity in Bolivia) birth cohort were analyzed. Rapid-growth during the first 6 months was defined as a change in weight z-score > 0.67 while slow-growth was defined as a weight z-score change of < −0.67. Neurodevelopment was evaluated using the Bayley Scales of Infant Development at 10.5–12.5 months of age. Mixed models were used to examine the association between cognitive development and weight gain.
Rapid growers weighed less at birth (P < 0.01). However, they revealed a higher body mass index at 12 months of age (0.70 ± 0.73, P < 0.01). After adjustment for confounding, rapid growth was not associated with cognitive development (coef = 0.49, 95% confidence interval = −4.10, 5.08).
In this Bolivian cohort, children born smaller were more likely to grow/develop faster and attain greater weight and length. Their cognitive development was not affected by their growth patterns. Am. J. Hum. Biol., 2013. © 2012 Wiley Periodicals, Inc.