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Child patterns of growth delay and cognitive development in a bolivian mining city

Authors

  • María Ruiz-Castell,

    Corresponding author
    1. Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Dr. Aiguader, 88 08003 Barcelona, Spain
    2. IRD-Bolivie-Institut de Recherche pour le Développement, Esq. Calle 7 Obrajes La Paz, Bolivia
    • Universitat Pompeu Fabra (UPF), Ramon Trias Fargas, 25-27; 08005 Barcelona, Spain
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  • Anne-Elie Carsin,

    1. Centre for Research in Environmental Epidemiology (CREAL), Barcelona Biomedical Research Park, Dr. Aiguader, 88 08003 Barcelona, Spain
    2. Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona Biomedical Research Park, Dr. Aiguader, 88 08003 Barcelona, Spain
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  • Flavia-Laura Barbieri,

    1. IRD-Bolivie-Institut de Recherche pour le Développement, Esq. Calle 7 Obrajes La Paz, Bolivia
    2. SELADIS-Servicios de Laboratorio de Investigación en Salud, Universidad Mayor de San Andrés (UMSA), Miraflores, LaPaz, Bolivia
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  • Pamela Paco,

    1. IRD-Bolivie-Institut de Recherche pour le Développement, Esq. Calle 7 Obrajes La Paz, Bolivia
    2. SELADIS-Servicios de Laboratorio de Investigación en Salud, Universidad Mayor de San Andrés (UMSA), Miraflores, LaPaz, Bolivia
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  • Jacques Gardon,

    1. IRD-HSM Montpellier-MSE, Place Eugène Bataillon 34095 Montpellier Cedex 5
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  • Jordi Sunyer

    1. Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Dr. Aiguader, 88 08003 Barcelona, Spain
    2. Centre for Research in Environmental Epidemiology (CREAL), Barcelona Biomedical Research Park, Dr. Aiguader, 88 08003 Barcelona, Spain
    3. Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona Biomedical Research Park, Dr. Aiguader, 88 08003 Barcelona, Spain
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Abstract

Objectives:

This study aims to (1) follow up and characterize infant growth patterns during the first year of life in Bolivia, and (2) determine whether there exists an association between weight gain and cognitive development in children living near contaminated mining industries.

Methods:

Data on 175 children participating to the ToxBol (Toxicity in Bolivia) birth cohort were analyzed. Rapid-growth during the first 6 months was defined as a change in weight z-score > 0.67 while slow-growth was defined as a weight z-score change of < −0.67. Neurodevelopment was evaluated using the Bayley Scales of Infant Development at 10.5–12.5 months of age. Mixed models were used to examine the association between cognitive development and weight gain.

Results:

Rapid growers weighed less at birth (P < 0.01). However, they revealed a higher body mass index at 12 months of age (0.70 ± 0.73, P < 0.01). After adjustment for confounding, rapid growth was not associated with cognitive development (coef = 0.49, 95% confidence interval = −4.10, 5.08).

Conclusions:

In this Bolivian cohort, children born smaller were more likely to grow/develop faster and attain greater weight and length. Their cognitive development was not affected by their growth patterns. Am. J. Hum. Biol., 2013. © 2012 Wiley Periodicals, Inc.

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