Occupational categories at risk for Parkinson's disease
Version of Record online: 25 MAY 2001
Copyright © 2001 Wiley-Liss, Inc.
American Journal of Industrial Medicine
Volume 39, Issue 6, pages 564–571, June 2001
How to Cite
Kirkey, K. L., Johnson, C. C., Rybicki, B. A., Peterson, E. L., Kortsha, G. X. and Gorell, J. M. (2001), Occupational categories at risk for Parkinson's disease. Am. J. Ind. Med., 39: 564–571. doi: 10.1002/ajim.1055
- Issue online: 25 MAY 2001
- Version of Record online: 25 MAY 2001
- Manuscript Accepted: 15 FEB 2001
- National Institute of Environmental Health Sciences. Grant Number: ES06418 and P03ES06639
- William T. Gossett Parkinson's Disease Center
- Louis Hayman Parkinson's Disease Research Fund
- Parkinson's disease;
- occupational coding;
- service occupations;
- agriculture occupations
The etiology of Parkinson's disease (PD) is considered to have a strong environmental component, but relatively few studies have investigated the potential association between occupation and the disease.
In a population-based case-control study, we collected comprehensive occupational histories from all study participants, 144 case and 464 control subjects.
Chi-square analysis revealed that working in an agricultural occupation increased estimated PD risk (OR = 1.74; 95% CI = 0.85, 3.60). In contrast, a history of ever working in a service occupation was negatively associated with PD risk (OR = 0.69; 95% CI = 0.47, 1.00). Risk estimates were close to one for specific service occupations. Adjusted odds ratios for all non-service occupational and industrial categories were similar, and working in a service occupation was the only significant inverse predictor of PD risk.
Future investigations focusing on lifestyle factors and environmental exposures within the agricultural and service occupational categories are warranted. Am. J. Ind. Med. 39:564–571, 2001. © 2001 Wiley-Liss, Inc.