Presented at the 4th Skokloster Workshop Conference: Organic Dusts—Agents, Disease and Prevention, Gothenburg, Sweden, April 7–10, 2003.
Atopic and non-atopic asthma in a farming and a general population†
Article first published online: 16 SEP 2004
Copyright © 2004 Wiley-Liss, Inc.
American Journal of Industrial Medicine
Volume 46, Issue 4, pages 396–399, October 2004
How to Cite
Eduard, W., Omenaas, E., Bakke, P. S., Douwes, J. and Heederik, D. (2004), Atopic and non-atopic asthma in a farming and a general population. Am. J. Ind. Med., 46: 396–399. doi: 10.1002/ajim.20088
- Issue published online: 16 SEP 2004
- Article first published online: 16 SEP 2004
- Manuscript Accepted: 23 JUL 2004
- fungal spores
In a previous study inverse associations between asthma and exposure to fungal spores and endotoxins in atopic farmers and positive associations with the same factors in non-atopic farmers were documented. No external reference population had been included. We, therefore, compared this farming population with the general population from an adjacent region.
Random samples of a farming (n = 2,106) and a rural (n = 351) and urban (n = 727) general population were selected. Atopy was assessed by serum IgE and asthma by questionnaires.
The asthma prevalence was 4.0% among farmers, 5.7% in the rural, and 7.6% in the urban population. Atopy was similar (9–10%). Most asthmatics were not atopic, 67–75%. Farmers had asthma less often than the general population OR 0.52 (95% CI 0.36–0.75); both atopic (OR 0.33 (95% CI 0.15–0.69)) and non-atopic asthma (OR 0.60 (95% CI 0.39–0.93)).
This may indicate a protective effect of the farm environment on asthma but a healthy worker effect may also play a role. Am. J. Ind. Med. 46:396–399, 2004. © 2004 Wiley-Liss, Inc.