Institution where work was performed: Department of Work Environment, School of Health and Environment, University of Massachusetts Lowell.
Job strain and autonomic indices of cardiovascular disease risk†
Article first published online: 10 AUG 2005
Copyright © 2005 Wiley-Liss, Inc.
American Journal of Industrial Medicine
Volume 48, Issue 3, pages 182–193, September 2005
How to Cite
Collins, S. M., Karasek, R. A. and Costas, K. (2005), Job strain and autonomic indices of cardiovascular disease risk. Am. J. Ind. Med., 48: 182–193. doi: 10.1002/ajim.20204
- Issue published online: 10 AUG 2005
- Article first published online: 10 AUG 2005
- Manuscript Accepted: 24 JUN 2005
- Chancellor's Research Fund
- Kerr Ergonomics Institute
- Department of Work Environment, School of Health and Environment, University of Massachusetts Lowell
- job strain;
- heart rate variability;
- job content questionnaire;
- psychosocial factors;
- occupational stress;
- cardiac disease risk
Despite the epidemiological evidence linking job strain to cardiovascular disease, more insight is needed into the etiologic mechanisms. This, in turn, would help to more precisely identify risk.
We measured Job Strain using the Job Content Questionnaire, 8/day diary reports, and nationally standardized occupational code linkage, as well as autonomic regulation utilizing heart rate variability including spectral-derived components and QT interval variability in 36 healthy mid-aged males with varying strain jobs. The subjects wore Holter-monitors for 48 hr; this included a work and rest day.
Job strain (P = 0.02) and low decision latitude (P = 0.004) were associated with a reduction in cardiac vagal control (HFP) persisting throughout the 48 hr. Job strain was also associated with elevations in sympathetic control during working hours (P = 0.003).
The disturbed cardiovascular regulatory pattern associated with job strain may help explain the increased risk of cardiovascular diseases linked with occupational exposure. Am. J. Ind. Med. 48:182–193, 2005. © 2005 Wiley-Liss, Inc.