SEARCH

SEARCH BY CITATION

Keywords:

  • cohort;
  • rubber tire;
  • cancer incidence;
  • cancer mortality;
  • respiratory cancer

Abstract

Background

A classification of 12 work categories was used to evaluate the cancer incidence and mortality among a cohort of Swedish rubber tire workers.

Methods

Cancer incidence and mortality in the cohort was compared with expected values from national rates. Standardized incidence and mortality ratios were calculated for the total cohort, for sub-cohorts and with the inclusion of a latency requirement.

Results

Among men, increased incidence and mortality risks were found for cancer in the larynx; SIR = 2.10; 95% confidence intervals (95% CI): 1.05–3.76, SMR = 2.08; 95% CI: 0.42–6.09. Increased risks were also seen for cancer in the trachea, bronchus, and lung; SIR = 1.62; 95% CI: 1.28–2.02, SMR = 1.54; 95% CI: 1.21–1.94, the incidence risk was highest among those with the longest exposure duration and among workers in compounding/mixing, milling, and maintenance. Decreased incidence risks were seen for cancer of the prostate (SIR = 0.74; 95% CI: 059–0.92) and skin (SIR = 0.57; 95% CI: 0.36–0.84).

Conclusions

The finding of an excess of tumors in the respiratory system is in agreement with earlier findings in other studies on rubber tire workers. The results on other cancer types are compared to earlier findings and related to work processes and chemical exposures of possible causal importance. Am. J. Ind. Med. 50:901–909, 2007. © 2007 Wiley-Liss, Inc.