Occupational immediate-type asthma and rhinitis due to rhodium salts
Article first published online: 1 DEC 2009
Copyright © 2009 Wiley-Liss, Inc.
American Journal of Industrial Medicine
Volume 53, Issue 1, pages 42–46, January 2010
How to Cite
Merget, R., Sander, I., van Kampen, V., Raulf-Heimsoth, M., Ulmer, H.-M., Kulzer, R. and Bruening, T. (2010), Occupational immediate-type asthma and rhinitis due to rhodium salts. Am. J. Ind. Med., 53: 42–46. doi: 10.1002/ajim.20786
- Issue published online: 16 DEC 2009
- Article first published online: 1 DEC 2009
- Manuscript Accepted: 9 OCT 2009
Whereas platinum salts are well known occupational allergens, rhodium salts have not been identified as inhalative sensitizing substances.
A 27-year-old atopic operator of an electroplating plant developed work-related shortness of breath and runny nose with sneezing after exposure to rhodium salts. Quantitative skin prick tests (SPT) and bronchial challenge tests with a dosimeter protocol were performed with quadrupling doses of the sodium chloride salts of rhodium (Na3RhCl6) and platinum (Na2PtCl6).
The patient showed positive SPT reactions and positive bronchial immediate-type reactions with rhodium and platinum salts. Sensitivity to rhodium salt was much higher than to platinum salt; the molar concentrations differed by a factor of 256 in SPT and a factor of 16 in bronchial challenges.
Rhodium salts should be considered as occupational immediate-type allergens. Am. J. Ind. Med. 53:42–46. 2010. © 2009 Wiley-Liss, Inc.