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Update of the NIOSH life table analysis system: A person-years analysis program for the windows computing environment

Authors

  • Mary K. Schubauer-Berigan PhD,

    Corresponding author
    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
    • Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS-R15, Cincinnati, OH 45226.
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  • Misty J. Hein PhD,

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • William M. Raudabaugh BS,

    1. Adivo Ltd., Dublin, Ohio
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  • Avima M. Ruder PhD,

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • Sharon R. Silver MS,

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • Steven Spaeth BS,

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • Kyle Steenland PhD,

    1. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia
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  • Martin R. Petersen PhD,

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • Kathleen M. Waters BS

    1. Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio
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  • Disclosure Statement: The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the National Institute for Occupational Safety and Health. Mention of trade names does not imply endorsement by the U.S. government.

Abstract

Background

Person-years analysis is a fundamental tool of occupational epidemiology. A life table analysis system (LTAS), previously developed by the National Institute for Occupational Safety and Health, was limited by its platform and analysis and reporting capabilities. We describe the updating of LTAS for the Windows operating system (LTAS.NET) with improved properties.

Software Development Process

A group of epidemiologists, programmers, and statisticians developed software, platform, and computing requirements. Statistical methods include the use of (indirectly) standardized mortality ratios, (directly) standardized rate ratios, confidence intervals, and P values based on the normal approximation and exact Poisson methods, and a trend estimator for linear exposure–response associations.

Software Features

We show examples using LTAS.NET to stratify and analyze multiple fixed and time-dependent variables. Data import, stratification, and reporting options are highly flexible. Users may export stratified data for Poisson regression modeling.

Conclusions

LTAS.NET incorporates improvements that will facilitate more complex person-years analysis of occupational cohort data. Am. J. Ind. Med. 54:915–924, 2011. © 2011 Wiley Periodicals, Inc.

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