Pleural mesothelioma mortality and asbestos exposure mapping in Italy

Authors

  • Lucia Fazzo MSc,

    Corresponding author
    1. Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
    • Unit of Environmental Epidemiology, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Viale Regina Elena, 299I- 00161 Rome, Italy.
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  • Marco De Santis BSc,

    1. Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
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  • Giada Minelli DrSci,

    1. Bureau of Statistics, National Center for Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, Rome, Italy
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  • Caterina Bruno MD,

    1. Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
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  • Amerigo Zona MD,

    1. Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
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  • Alessandro Marinaccio DrSci,

    1. Epidemiology Unit, Department of Occupational Medicine, Italian National Institute for Occupational Safety and Prevention, Rome, Italy
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  • Susanna Conti DrSci,

    1. Bureau of Statistics, National Center for Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, Rome, Italy
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  • Pietro Comba PhD

    1. Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy
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  • Disclosure statement: The authors report no conflicts of interests.

Abstract

Background

An epidemic of asbestos-related diseases is ongoing worldwide. Mortality from malignant pleural neoplasms in Italy was analyzed, to estimate the health impact of asbestos at national and local level.

Methods

Mortality from ICD-9 code 163 was considered, in the time-window 1995–2002, using National Bureau of Statistics data. National and regional standardized rates and municipal Standardized Mortality Ratios (SMR) were calculated. Municipal clusters were identified by applying Spatial Scan Statistics procedure. Relative risks (RR) express the ratio of risk within the cluster to the risk outside the cluster.

Results

The national standardized annual mortality rate was 1.9 per 100,000. Significant clusters corresponded to asbestos-cement industries (Casale Monferrato: RR = 11.63), shipyards (Monfalcone, RR = 7.43), oil refineries (Falconara, RR = 2.52), petrochemical industries (Priolo, RR = 3.81).

Conclusions

The present study confirms malignant pleural neoplasms mortality as a suitable indicator of asbestos exposure at geographic level. In addition to asbestos-cement industries and shipyards, other industrial settings are associated with pleural neoplasm mortality. Am. J. Ind. Med. 55:11–24, 2012. © 2011 Wiley Periodicals, Inc.

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