All-cause mortality and cancer incidence among adults exposed to blue asbestos during childhood

Authors

  • Alison Reid BSc, MSc, PhD,

    Corresponding author
    1. Western Australian Institute for Medical Research, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia
    2. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
    • Western Australian Institute for Medical Research, M519, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009.
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  • Peter Franklin BSc(Hons), Postgrad Dip Env Sci, PhD,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
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  • Nola Olsen B Appl Science, RGN,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
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  • Jan Sleith,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
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  • Latha Samuel BEng, Postgrad Dip IT,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
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  • Patrick Aboagye-Sarfo BSc, MMath, MStat, PhD,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
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  • Nicholas de Klerk BSc, MSc, PhD,

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
    2. Telethon Institute for Child Health Research, Subiaco, Western Australia, Australia
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  • A.W. (Bill) Musk MBBS, FRACP, MD

    1. School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
    2. Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
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  • Disclosure Statement: The authors report no conflicts of interests.

Abstract

Background

There are few data on the long-term health outcomes of exposure to asbestos in childhood. This study investigated cancer and mortality of adults exposed to blue asbestos as children.

Methods

Data linkage to relevant health registries was used to identify cancers and mortality in a cohort of adults (n = 2,460) that had lived in an asbestos mining town during their childhood (<15 years).

Results

There were 217 (93 female) incident cancers and 218 (70 female) deaths among the cohort. Compared with the Western Australian population females had elevated mesothelioma, ovarian and brain cancers, and increased “all cause” and “all cancer” mortality. Males had elevated mesothelioma, leukemia, prostate, brain, and colorectal cancers, and excess mortality from “all causes,” “all cancers,” circulatory disease, diseases of the nervous system, and accidents.

Conclusion

Exposure to blue asbestos in childhood is associated with an increased risk of cancer and mortality in adults. Am. J. Ind. Med. 56:133–145, 2013. © 2011 Wiley Periodicals, Inc.

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