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Keywords:

  • bioaerosols;
  • exposure–response;
  • tolerance;
  • respiratory symptoms;
  • lung function

Objectives

The aim of the study was to determine exposure–response relationships in salmon-processing workers.

Methods

Cross-shift FEV1, acute respiratory symptoms, and exposure to total protein, parvalbumin and endotoxin were main variables measured during one workweek. Exposure–response relationships were analyzed by Generalized Estimation Equations of cross-week data and by multiple regressions of day-to-day data.

Results

Exposure levels were higher in those workers who reported use of water hose. GEE showed negative coefficients for interaction between TP exposure and time (days) on cross-week change of FEV1. Multiple regressions showed significant associations between TP levels and cross-shift change of FEV1 and symptoms (cough, chest tightness) only for Monday shifts.

Conclusions

A tolerance effect during the course of a workweek is suggested. Use of water hose is a risk process with regard to the liberation of measured components of bioaerosols. Am. J. Ind. Med. 57:276–285, 2014. © 2013 Wiley Periodicals, Inc.