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Cytogenetics and molecular genetics of bladder cancer: A personal view

Authors

  • Avery A. Sandberg

    Corresponding author
    • Department of DNA Diagnostics, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013.
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    • Avery A. Sandberg, M.D., D.Sc., is Editor-in-Chief of Cancer Genetics and Cytogenetics; Clinical Consultant in the Department of DNA Diagnostics at St. Joseph's Hospital and Medical Center in Phoenix, Arizona; and Clinical Professor in Pathology at the University of Arizona in Tucson, Arizona.


Abstract

The cytogenetic and molecular genetic aspects that may be involved in the pathogenesis of bladder cancer are presented. Although anomalies of chromosome 9 may play an initial causative role in this cancer, the subsequent events, involving a succession of genetic changes, are less established or understood. This presentation is a distillation of what generally are considered to be the cytogenetic and molecular genetic events that constitute the array of changes underlying bladder cancer. © 2002 Wiley-Liss, Inc.

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