Genetic counseling in Becker type X-linked muscular dystrophy. I. Theoretical considerations



The prior probability of any woman being a carrier for Becker muscular dystrophy (BMD) has been calculated. If μ is the mutation rate in female germ cells and n̈ the mutation rate in male germ cells, this probability is 34/3μ + 20/3v. For all X-linked diseases with a fitness f the prior probability (H) is:

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