Article

Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia

  1. S. Fox,
  2. M. Bloch,
  3. M. Fahy,
  4. M. R. Hayden*

Article first published online: 3 JUN 2005

DOI: 10.1002/ajmg.1320320214

Issue

American Journal of Medical Genetics

American Journal of Medical Genetics

Volume 32, Issue 2, pages 211–216, February 1989

Additional Information

How to Cite

Fox, S., Bloch, M., Fahy, M. and Hayden, M. R. (1989), Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia. Am. J. Med. Genet., 32: 211–216. doi: 10.1002/ajmg.1320320214

Author Information

  1. Department of Medical Genetics, University of British Columbia, Vancouver, Canada

*Department of Medical Genetics, Room F168 - University Hospital, 2211 Wesbrook Mall, Vancouver, BC V6T 2B5

Publication History

  1. Issue published online: 3 JUN 2005
  2. Article first published online: 3 JUN 2005
  3. Manuscript Revised: 9 SEP 1988
  4. Manuscript Received: 13 MAY 1988

Funded by

  • NHRDP, the Woodward Foundation, and the Huntington Society of Canada

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Keywords:

  • psychosocial assessment;
  • genetic counseling;
  • DNA analysis

Abstract

The discovery of DNA markers linked to the gene causing Huntington disease (HD) has allowed the development of predictive testing programs for persons at-risk. A pilot program was established in British Columbia in November 1986. Ninetyfive persons are currently enrolled. The major objective of this project is to introduce and evaluate a protocol for the delivery of test results to persons at-risk for HD. The criteria for entry and details of the psychosocial assessment before and after receiving a modified risk are presented. The guidelines that are developed from this project will have major applications for predictive testing programs for other late onset autosomal dominant disorders.

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