Article

Rhesus sensitization after midtrimester genetic amniocentesis

  1. H. Brandenburg M.D.1,*,
  2. M. G. J. Jahoda2,
  3. L. Pijpers1,
  4. J. W. Wladimiroff2,
  5. John M. Opitz Editor,
  6. James F. Reynolds Editor

Article first published online: 3 JUN 2005

DOI: 10.1002/ajmg.1320320216

Issue

American Journal of Medical Genetics

American Journal of Medical Genetics

Volume 32, Issue 2, pages 225–226, February 1989

Additional Information

How to Cite

Brandenburg, H., Jahoda, M. G. J., Pijpers, L., Wladimiroff, J. W., Opitz, J. M. and Reynolds, J. F. (1989), Rhesus sensitization after midtrimester genetic amniocentesis. Am. J. Med. Genet., 32: 225–226. doi: 10.1002/ajmg.1320320216

Author Information

  1. 1

    Departments of Clinical Genetics Academic Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands

  2. 2

    Obstetrics and Gynecology Academic Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands

*Dept. of Obstetrics and Gynecology, Academic Hospital Dijkzigt, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands

Publication History

  1. Issue published online: 3 JUN 2005
  2. Article first published online: 3 JUN 2005
  3. Manuscript Revised: 22 AUG 1988
  4. Manuscript Received: 18 MAY 1988

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Keywords:

  • rhesus immunization;
  • rhesus immunoglobulin;
  • anti-D;
  • fetal loss following amniocentesis;
  • complication of amniocentesis;
  • fetal maternal transfusion;
  • prevention of Rh sensitization

Abstract

In 944 Rh-negative patients who received rhesus immunoglobulin (anti-D) following genetic amniocentesis, not a single case of Rh sensitization occurred. Routine administration of a small dose (100 μg) of anti-D is effective in preventing Rh sensitization after midtrimester amniocentesis.

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