Article

Neoplasms in proteus syndrome

  1. Patricia L. Gordon1,
  2. R. Sid Wilroy1,
  3. Olga E. Lasater2,
  4. Dr. M. Cohen Michael Jr.3,*

Article first published online: 9 JUN 2005

DOI: 10.1002/ajmg.1320570117

Issue

American Journal of Medical Genetics

American Journal of Medical Genetics

Volume 57, Issue 1, pages 74–78, 22 May 1995

Additional Information

How to Cite

Gordon, P. L., Wilroy, R. S., Lasater, O. E. and Michael, M. C. (1995), Neoplasms in proteus syndrome. Am. J. Med. Genet., 57: 74–78. doi: 10.1002/ajmg.1320570117

Author Information

  1. 1

    Division of Genetics, University of Tennessee, Memphis, Tennessee

  2. 2

    Department of Pediatric Pathology, University of Tennessee, Memphis, Tennessee

  3. 3

    Department of Oral Biology, Faculty of Dentistry and Department of Pediatrics, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

*Dalhousie University, Halifax, Nova Scotia B3H 3J5, Canada

Publication History

  1. Issue published online: 9 JUN 2005
  2. Article first published online: 9 JUN 2005
  3. Manuscript Revised: 1 DEC 1994
  4. Manuscript Received: 17 AUG 1994

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Keywords:

  • tumors;
  • mesothelioma;
  • serous cystadenoma

Abstract

We report on 2 children with Proteus syndrome who developed neoplasms. Patient 1 had a probable mesothelioma, although papillary carcinoma of the thyroid could not be completely ruled out. Patient 2 had bilateral ovarian serous cystadenomas with nuclear atypia. Other unusual neoplasms in Proteus syndrome are discussed, together with their etiologic and pathogenetic possibilities. © 1995 Wiley-Liss, Inc.

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