Vascular update: Morphogenesis, tumors, malformations, and molecular dimensions

Authors

  • M. Michael Cohen Jr.

    Corresponding author
    1. Department of Pediatrics, Dalhousie University, 5981 University Ave., Halifax, Nova Scotia B3H 1W2
    • Department of Pediatrics, Dalhousie University, 5981 University Ave., Halifax, Nova Scotia B3H 1W2.
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  • How to cite this article: Cohen MM Jr. 2006. Vascular update: Morphogenesis, tumors, malformations, and molecular dimensions. Am J Med Genet Part A 140A:2013–2038.

Abstract

This vascular review is organized under the following headings: vasculogenesis and angiogenesis; vascular endothelial growth factors, their receptors, TIE receptors, and angiopoietins; other factors in blood vessel formation; parallel patterning in blood vessels and nerves; physiological and pathological neovascularization; the role of VEGF receptors in metastasis; anti-angiogenic therapy for tumors; association of blood vessels with fat; vascular malformations and vascular tumors; infantile hemangiomas; congenital hemangiomas; lymphatic malformations; molecular characteristics of some disorders with vascular malformations; Kasabach-Merritt phenomenon; Sturge-Weber syndrome, Klippel-Trenaunay syndrome, and Parkes Weber syndrome; diagnostic and laboratory studies; and future perspectives. © 2006 Wiley-Liss, Inc.

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