How to cite this article: Angkustsiri K, Wirojanan J, Deprey LJ, Gane LW, Hagerman RJ. 2008. Fragile X syndrome with anxiety disorder and exceptional verbal intelligence. Am J Med Genet Part A 146A:376–379.
Fragile X syndrome with anxiety disorder and exceptional verbal intelligence†
Article first published online: 17 JAN 2008
Copyright © 2008 Wiley-Liss, Inc.
American Journal of Medical Genetics Part A
Volume 146A, Issue 3, pages 376–379, 1 February 2008
How to Cite
Angkustsiri, K., Wirojanan, J., Deprey, L. J., Gane, L. W. and Hagerman, R. J. (2008), Fragile X syndrome with anxiety disorder and exceptional verbal intelligence. Am. J. Med. Genet., 146A: 376–379. doi: 10.1002/ajmg.a.32118
- Issue published online: 25 JAN 2008
- Article first published online: 17 JAN 2008
- Manuscript Accepted: 23 AUG 2007
- Manuscript Received: 8 NOV 2006
- NICHD. Grant Numbers: HD036071, HD02274
- NINDS. Grant Number: NS044299
- Center for Disease Control and Prevention. Grant Number: U10/CCU925123
- fragile X syndrome;
- anxiety disorder;
- verbal intelligence
Fragile X syndrome (FXS) is often characterized by mental retardation. However, FXS is also associated with significant emotional and psychiatric problems, including anxiety, depression, attention difficulties, and learning disabilities in the presence of a normal IQ. This report describes a unique woman with the full mutation of FXS who has an exceptional profile of above-average intelligence combined with significant impairments due to anxiety and learning disability. Women with FXS can present primarily with learning and emotional problems, and clinicians should consider FXS in these women regardless of their IQ. © 2008 Wiley-Liss, Inc.