How to cite this article: DiGiovanna JJ, Priolo M, Itin P. 2009. Approach towards a new classification for ectodermal dysplasias: Integration of the clinical and molecular knowledge. Am J Med Genet Part A 149A:2068–2070.
Approach towards a new classification for ectodermal dysplasias: Integration of the clinical and molecular knowledge†
Version of Record online: 13 AUG 2009
Copyright © 2009 Wiley-Liss, Inc.
American Journal of Medical Genetics Part A
Special Issue: Ankyloblepharon-Ectodermal Defects-Cleft Lip and/or Palate Syndrome and Ectodermal Dysplasias
Volume 149A, Issue 9, pages 2068–2070, September 2009
How to Cite
DiGiovanna, J. J., Priolo, M. and Itin, P. (2009), Approach towards a new classification for ectodermal dysplasias: Integration of the clinical and molecular knowledge. Am. J. Med. Genet., 149A: 2068–2070. doi: 10.1002/ajmg.a.32961
- Issue online: 20 AUG 2009
- Version of Record online: 13 AUG 2009
- Manuscript Accepted: 14 MAY 2009
- Manuscript Received: 10 FEB 2009
- ectodermal dysplasia;
Rapid advances in new basic knowledge have led to a greater understanding of the genetic, embryologic, molecular biologic, and functional mechanisms underlying the ectodermal dysplasias. Scientists, researchers, and clinicians from diverse fields desire a classification that meets the needs of these rapidly changing concepts which, in addition to being clinically useful, can help further advances in understanding the basic underlying mechanisms, and can also spur the development of new therapies. The currently used classification was designed for clinical utility and has not easily integrated with the new concepts. Various users have suggested that a new classification should be based on underlying genetic and molecular abnormality, functional mechanism, embryology, or clinical features. The goal of this conference was to advance towards a consensus and this manuscript is a summary of a workshop focused on an approach towards the development of a classification that integrates the clinical and molecular knowledge. © 2009 Wiley-Liss, Inc.