How to cite this article: Nelson RA, McNamara M, Ellis W, Stein-Wexler R, Moghaddam B, Zwerdling T. 2009. Floating–Harbor syndrome and intramedullary spinal cord ganglioglioma: Case report and observations from the literature. Am J Med Genet Part A 149A:2265–2269.
Floating–Harbor syndrome and intramedullary spinal cord ganglioglioma: Case report and observations from the literature†
Article first published online: 16 SEP 2009
Copyright © 2009 Wiley-Liss, Inc.
American Journal of Medical Genetics Part A
Volume 149A, Issue 10, pages 2265–2269, October 2009
How to Cite
Nelson, R. A., McNamara, M., Ellis, W., Stein-Wexler, R., Moghaddam, B. and Zwerdling, T. (2009), Floating–Harbor syndrome and intramedullary spinal cord ganglioglioma: Case report and observations from the literature. Am. J. Med. Genet., 149A: 2265–2269. doi: 10.1002/ajmg.a.33014
- Issue published online: 24 SEP 2009
- Article first published online: 16 SEP 2009
- Manuscript Accepted: 17 JUN 2009
- Manuscript Received: 27 JAN 2009
- delayed bone age;
- speech delay;
- Floating–Harbor syndrome;
- spinal cord neoplasms;
- mental retardation;
- short stature
We report on a 5-year-old male with expressive language delay, developmental delay, short stature, and facial anomalies consistent with Floating–Harbor syndrome (FHS). In addition, he developed an intramedullary ganglioglioma. This is the first reported case of a tumor associated with FHS, and may represent an as yet undefined genetic link between spinal cord tumors and FHS, adding this syndrome to the growing list of disorders with a predisposition for tumor development. © 2009 Wiley-Liss, Inc.