How to cite this article: Hens K, Nys H, Cassiman J-J, Dierickx K. 2009. Genetic research on stored tissue samples from minors: A systematic review of the ethical literature. Am J Med Genet Part A 149A:2346–2358.
Genetic research on stored tissue samples from minors: A systematic review of the ethical literature†
Article first published online: 16 SEP 2009
Copyright © 2009 Wiley-Liss, Inc.
American Journal of Medical Genetics Part A
Volume 149A, Issue 10, pages 2346–2358, October 2009
How to Cite
Hens, K., Nys, H., Cassiman, J.-J. and Dierickx, K. (2009), Genetic research on stored tissue samples from minors: A systematic review of the ethical literature. Am. J. Med. Genet., 149A: 2346–2358. doi: 10.1002/ajmg.a.33032
- Issue published online: 24 SEP 2009
- Article first published online: 16 SEP 2009
- Manuscript Accepted: 1 JUL 2009
- Manuscript Received: 18 DEC 2008
- GeneBanC. Grant Number: 036751
- FWO Flanders. Grant Number: G029107
- Eurogentest Network of Excellence of the EU. Grant Number: FP-512148
- literature review;
- genetic research;
- biological sample;
- minimal risk;
The potential benefits of biobank research are well known. Also, the ethical implications of genetic research on stored tissue samples are well discussed in existing literature. The inclusion of tissue samples from minors may have significant scientific value. However, this inclusion raises specific ethical questions. We have performed a systematic search of the literature and found 21 theoretical and empirical articles dealing with the issue. After review, we distilled five clusters of themes: consent, risks, benefits, return of results, and ownership. We have described the different components of these themes, as they occurred in the literature and have provided a discourse on the topic. © 2009 Wiley-Liss, Inc.