Additional supporting information may be found in the online version of this article.

AJMG_34176_sm_Suppl-Fig-1.tif517KFig. 1: G-banded metaphase. Arrow indicates supernumerary isochromosome 9p.
AJMG_34176_sm_Suppl-Fig-2.tif296KFig. 2: Metaphase FISH image with whole chromosome-9 specific painting probe labeled with FITC. Small arrows indicate normal homologues of chromosome 9 and large arrow indicates supernumerary isochromosome 9p, which hybridized to the FISH probe along its entire length.

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