How to Cite this Article: Alfieri P, Cesarini L, De Rose P, Ricci D, Selicorni A, Guzzetta A, Baranello G, Tinelli F, Mallardi M, Zampino G, Vicari S, Atkinson J, Mercuri E. 2011. Visual processing in Noonan syndrome: Dorsal and ventral stream sensitivity. Am J Med Genet Part A 155:2459–2464.
Visual processing in Noonan syndrome: Dorsal and ventral stream sensitivity†
Article first published online: 9 SEP 2011
Copyright © 2011 Wiley-Liss, Inc.
American Journal of Medical Genetics Part A
Volume 155, Issue 10, pages 2459–2464, October 2011
How to Cite
Alfieri, P., Cesarini, L., De Rose, P., Ricci, D., Selicorni, A., Menghini, D., Guzzetta, A., Baranello, G., Tinelli, F., Mallardi, M., Zampino, G., Vicari, S., Atkinson, J. and Mercuri, E. (2011), Visual processing in Noonan syndrome: Dorsal and ventral stream sensitivity. Am. J. Med. Genet., 155: 2459–2464. doi: 10.1002/ajmg.a.34229
- Issue published online: 20 SEP 2011
- Article first published online: 9 SEP 2011
- Manuscript Accepted: 30 JUN 2011
- Manuscript Received: 10 NOV 2009
- Noonan syndrome;
- visual processing;
- ventral stream;
- dorsal stream;
- visuomotor skills
Global spatial and motion processing abilities were assessed in 18 patients with Noonan syndrome (NS) and in 43 matched controls using form and motion coherence testing, respectively. We observed a discrepancy between the two groups since the study group had significantly lower performances than the control group for form coherence while there was no impairment on motion coherence. All the patients were also assessed on the Movement Assessment Battery for Children (M-ABC) to evaluate visuomotor skills. Thirteen of the 18 (72%) also had global poor performances on the M-ABC. The results show that children with NS have a specific impairment in the global processing of visuospatial information and are likely to have a specific ventral stream deficit as also suggested by the frequent visuomotor perceptual difficulties. Testing form and motion coherence thresholds may be a useful diagnostic tool for this group of patients, despite their normal cognitive abilities, since aspects of global form processing and visuomotor perceptual difficulties can be identified and potentially targeted for a specific rehabilitation program. © 2011 Wiley-Liss, Inc.