How to Cite this Article: Ross LF. 2012. A re-examination of the use of ethnicity in prenatal carrier testing. Am J Med Genet Part A 158A:19–23.
A re-examination of the use of ethnicity in prenatal carrier testing†
Article first published online: 21 NOV 2011
Copyright © 2011 Wiley Periodicals, Inc.
American Journal of Medical Genetics Part A
Volume 158A, Issue 1, pages 19–23, January 2012
How to Cite
Ross, L. F. (2012), A re-examination of the use of ethnicity in prenatal carrier testing. Am. J. Med. Genet., 158A: 19–23. doi: 10.1002/ajmg.a.34361
- Issue published online: 19 DEC 2011
- Article first published online: 21 NOV 2011
- Manuscript Accepted: 29 SEP 2011
- Manuscript Received: 30 JUL 2011
- Greenwall Foundation (partly)
- carrier testing;
- prenatal testing;
- heterozygote detection;
- cystic fibrosis;
- sickle cell disease;
- Tay-Sachs disease
In April 2011, the American Congress of Obstetricians and Gynecologists (formerly the American College of Obstetrics and Gynecology [ACOG]), updated its policy on carrier screening for cystic fibrosis and proposed that because of the increasing difficulty in assigning a single ethnicity to individuals, “It is reasonable, therefore to offer CF carrier screening to all patients.” However, ACOG continues to use ethnicity in its guidelines about carrier testing for autosomal recessive disorders like sickle cell disease (SCD) and Tay-Sachs disease (TSD). This practice is in marked contrast with newborn screening (NBS) which is universally provided for all conditions. In this manuscript, I evaluate the discrepant role of ethnicity in NBS and carrier screening. I argue that ACOG needs to adopt the position it now takes for CF regarding prenatal carrier testing for all conditions. To promote equity in prenatal testing decision making, health care policies must acknowledge the diversity of the populations that we serve and empower all women and couples to make more fully informed reproductive decisions by offering prenatal carrier testing to all. © 2011 Wiley Periodicals, Inc.