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Additional supporting information may be found in the online version of this article.

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ajmg_35534_sm_SupplFigS1.tif64KeFig. 1: Weight curves in individuals with Costello syndrome after first exposure to GH from age 36 months to 120 months (dashed lines), compared to weight curves in individuals with Costello syndrome naïve to GH (solid lines). Note limited amount of data used to generate these curves, as outlined in the discussion.
ajmg_35534_sm_SupplFigS2.tif61KeFig. 2: Height curves in individuals with Costello syndrome after first exposure to GH from age 36 months to 120 months (dashed lines), compared to height curves in individuals with Costello syndrome naïve to GH (solid lines). Note limited amount of data used to generate these curves, as outlined in the discussion.

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