Sleep-disordered breathing in Beckwith–Wiedemann syndrome: Three patients


  • How to Cite this Article: Kansagra S, D'Cruz O, Noah TL, Vaughn BV. 2012. Sleep-disordered breathing in Beckwith–Wiedemann syndrome: Three patients. Am J Med Genet Part A 158A: 2956–2958.

  • Conflict of Interest Statement: None of the contributors have any potential conflicts of interest.


Beckwith–Wiedemann syndrome is associated with craniofacial abnormalities that may predispose patients to sleep-related breathing disorders. There is limited literature on the polysomnography findings for children with this syndrome. Three patients with Beckwith–Wiedemann syndrome underwent polysomnography in our sleep lab and were found to have a variety of sleep-disordered breathing that ranged from obstructive apnea to isolated REM sleep-related hypoxemia–hypoventilation without obstructive apnea. Suspicion for sleep-disordered breathing should be high in children with Beckwith–Wiedemann syndrome. © 2012 Wiley Periodicals, Inc.