Conflict of interest: none.
Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome
Article first published online: 10 JUL 2013
Copyright © 2013 Wiley Periodicals, Inc.
American Journal of Medical Genetics Part A
Volume 161, Issue 8, pages 1866–1874, August 2013
How to Cite
2013. Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome. Am J Med Genet Part A. 161A:1866–1874., , , , , , , , , , , .
- Issue published online: 24 JUL 2013
- Article first published online: 10 JUL 2013
- Manuscript Accepted: 8 APR 2013
- Manuscript Received: 18 OCT 2012
- Research Support Funds
- Undergraduate Research Opportunity
- Beaty-C/Tech Fund–Blue River Community Foundation
- National Science Foundation GK-12 Urban Educators Program at IUPUI NSF. Grant Number: DGE0742475
- National Institutes of Health. Grant Number: DE021034
Additional supporting information may be found in the online version of this article at the publisher's web-site.
FIG. S1. Representative parasagittal section of E13.5 embryo with structural identification.
FIG. S2. Localization of Meckel's and Hyoid Cartilages in E13.5 embryos.
FIG. S3. Biological functions of dysregulated genes in E13.5 mandibular precursor.
FIG. S4. Expression of Sox9 in euploid and trisomic Meckel's and Hyoid cartilages.
FIG. S5. DAPI Intensity correlates with Sox9 expression.
TABLE S3. Significant Functional Annotation Clusters as Found by DAVID.
TABLE S4a. Pathgen Linkage of Hsa21 and 20 Homeobox Genes and Sox9.
TABLE S4b. Pathgen Linkage of Hsa21 and 20 Homeobox Genes and Sox9.
TABLE S1. Microarray Results: 155 Statistically Significant Probe Sets After FDR Correction.
TABLE S2. Microarray Results: 75 Statistically Significant Probe Sets After Holms Correction.
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