Please cite this article as follows: Sjöberg RL, Nilsson KW, Wargelius H-L, Leppert J, Lindström L, Oreland L. 2006. Adolescent Girls and Criminal Activity: Role of MAOA-LPR Genotype and Psychosocial Factors. Am J Med Genet Part B 144B:159–164.
Adolescent girls and criminal activity: Role of MAOA-LPR genotype and psychosocial factors†
Article first published online: 10 OCT 2006
Copyright © 2006 Wiley-Liss, Inc.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Volume 144B, Issue 2, pages 159–164, 5 March 2007
How to Cite
Sjöberg, R. L., Nilsson, K. W., Wargelius, H.-L., Leppert, J., Lindström, L. and Oreland, L. (2007), Adolescent girls and criminal activity: Role of MAOA-LPR genotype and psychosocial factors. Am. J. Med. Genet., 144B: 159–164. doi: 10.1002/ajmg.b.30360
- Issue published online: 22 FEB 2007
- Article first published online: 10 OCT 2006
- Manuscript Accepted: 20 APR 2006
- Manuscript Received: 8 SEP 2005
- Uppsala University
- VR. Grant Number: 4021
- Swedish Brain Foundation
- Mobilizations against narcotics (MOB)
- The County Council of Västmanland
- monoamine oxidase;
- sex characteristics;
- social support;
Recent findings among boys show that interactions between a polymorphism in the monoamine oxidase A gene promoter region (MAOA-LPR) and psychosocial factors predict criminal activity. The objective of this study was to investigate whether this finding could be extended to adolescent girls. One hundred nineteen female adolescents were recruited among respondents to a cross-sectional study of the total population of 16- and 19-year old girls. These girls constituted a randomly selected sub-sample from groups representing different degrees of risk behavior. The subjects filled in a questionnaire and were interviewed and genotyped with regard to MAOA-LPR. The results indicate that the long, (4-repeat) allele confer an increased risk for criminal behavior in the presence of psychosocial risk. Among girls without social risk, MAOA-LPR genotype was of no importance for criminal behavior. The present results suggest that previous observations on adolescent males, which demonstrate that the short MAOA-LPR genotype and psychosocial adversity interact to predict criminal activity, may not be applicable to females. © 2006 Wiley-Liss, Inc.