How to Cite this Article: Deng X, Takaki H, Wang L, Kuroki T, Nakahara T, Hashimoto K, Ninomiya H, Arinami T, Inada T, Hiroshi U, Itokawa M, Tochigi M, Watanabe Y, Someya T, Kunugi H, Iwata N, Ozaki N, Shibata H, Fukumaki Y. 2011. Positive Association of Phencyclidine-Responsive Genes, PDE4A and PLAT, With Schizophrenia. Am J Med Genet Part B 156:850–858.
Positive association of Phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia†
Article first published online: 23 AUG 2011
Copyright © 2011 Wiley-Liss, Inc.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Volume 156, Issue 7, pages 850–858, December 2011
How to Cite
Deng, X., Takaki, H., Wang, L., Kuroki, T., Nakahara, T., Hashimoto, K., Ninomiya, H., Arinami, T., Inada, T., Ujike, H., Itokawa, M., Tochigi, M., Watanabe, Y., Someya, T., Kunugi, H., Iwata, N., Ozaki, N., Shibata, H. and Fukumaki, Y. (2011), Positive association of Phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia. Am. J. Med. Genet., 156: 850–858. doi: 10.1002/ajmg.b.31233
- Issue published online: 6 SEP 2011
- Article first published online: 23 AUG 2011
- Manuscript Accepted: 28 JUL 2011
- Manuscript Received: 19 DEC 2010
- Japan Society for the Promotion of Science (JSPS) for Young Scientists
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Naito Foundation Subsidy for Natural Science Researches
Additional Supporting information may be found in the online version of this article.
|ajmg_31233_sm_suppFig1.tif||1520K||Supplementary FIG. 1. Linkage Disequilibrium of SNPs distributed in seven gene regions. The magnitude of linkage disequilibrium (LD) was evaluated by calculating D' using the haplotype frequencies estimated by the Haploview program. The relative location of markers used to construct the haplotypes is represented on the upper parts of the panel, and is more clearly depicted in Figure 2. Each cell represents D' for the corresponding two-SNP combination with 5-grade color coding (darker is stronger in LD).|
|ajmg_31233_sm_suppTab1.doc||97K||Supplementary Table I. PCR primers for genotyping SNPs in the PCP-responsible genes|
|ajmg_31233_sm_suppTab2.doc||179K||Supplementary Table II. Gene expression change in five brain regions induced by PCP administration.|
|ajmg_31233_sm_suppTab3.doc||224K||Supplementary Table III. Association analyses of SNPs in PCP-responsive genes using the Screening Sample Set.|
|ajmg_31233_sm_suppTab4.doc||46K||Supplementary Table IV. Haplotype frequencies of the associated SNPS in PDE4A.|
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