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  • Allen NC, Bagade S, McQueen MB, Ioannidis JPA, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L. 2008. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database. Nat Genet 40: 827834.
  • American Psychiatric Association 1987. Diagnostic and statistical manual of mental disorders, 3rd edition “Revised”. Washington, DC: American Psychiatric Association.
  • American Psychiatric Association 1995. Diagnostic and statistical manual of mental disorders, 4th edition “International Version”. Washington, DC: American Psychiatric Association.
  • Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML, Depaulo JR, Kelsoe JR Jr, Rietschel M, Nothen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Schulze TG, McMahon FJ, Potash JB, Zandi PP. 2011. Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet Part B Neuropsychiatr Genet 156B: 370378.
  • Bottiglieri T, Laundy M, Crellin R, Toone BK, Carney MW, Reynolds EH. 2000. Homocysteine, folate, methylation, and monoamine metabolism in depression. J Neurol Neurosurg Psychiatry 69: 228232.
  • Demontis D, Nyegaard M, Buttenschon HN, Hedemand A, Pedersen CB, Grove J, Flint TJ, Nordentoft M, Werge T, Hougaard DM, Sorensen KM, Yolken RH, Mors O, Borglum AD, Mortensen PB. 2011. Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk. Am J Med Genet Part B Neuropsychiatr Genet 156B: 913922.
  • Frankenburg FR. 2007. The role of one-carbon metabolism in schizophrenia and depression. Harv Rev Psychiatry 15: 146160.
  • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuve LP, Rozen R. 1995. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 10: 111113.
  • Goff DC, Bottiglieri T, Arning E, Shih V, Freudenreich O, Evins AE, Henderson DC, Baer L, Coyle J. 2004. Folate, homocysteine, and negative symptoms in schizophrenia. Am J Psychiatry 161: 17051708.
  • Hansen T, Olsen L, Lindow M, Jakobsen KD, Ullum H, Jonsson E, Andreassen OA, Djurovic S, Mjelle I, Agartz I, Hall H, Timm S, Wang AG, Werge T. 2007. Brain expressed microRNAs implicated in schizophrenia etiology. PLoS ONE 2: e873.
  • Hazra A, Kraft P, Lazarus R, Chen C, Chanock SJ, Jacques P, Selhub J, Hunter DJ. 2009. Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Hum Mol Genet 18: 46774687.
  • Herran A, Garcia-Unzueta MT, Amado JA, Lopez-Cordovilla JJ, Diez-Manrique JF, Vazquez-Barquero JL. 1999. Folate levels in psychiatric outpatients. Psychiatry Clin Neurosci 53: 531533.
  • Hill M, Shannahan K, Jasinski S, Macklin EA, Raeke L, Roffman JL, Goff DC. 2011. Folate supplementation in schizophrenia: A possible role for MTHFR genotype. Schizophr Res 127: 4145.
  • Hollegaard MV, Thorsen P, Norgaard-Pedersen B, Hougaard DM. 2009. Genotyping whole-genome-amplified DNA from 3- to 25-year-old neonatal dried blood spot samples with reference to fresh genomic DNA. Electrophoresis 30: 25322535.
  • Jönsson EG, Larsson K, Vares M, Hansen T, Wang AG, Djurovic S, Rønningen KS, Andreassen OA, Agartz I, Werge T, Terenius L, Hall H. 2008. Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: An association study. Am J Med Genet Part B Neuropsychiatr Genet 147B: 976982.
  • Joober R, Benkelfat C, Lal S, Bloom D, Labelle A, Lalonde P, Turecki G, Rozen R, Rouleau GA. 2000. Association between the methylenetetrahydrofolate reductase 677C–>T missense mutation and schizophrenia. Mol Psychiatry 5: 323326.
  • Kähler A, Djurovic S, Kulle B, Jönsson EG, Agartz I, Hall H, Opjordsmoen S, Jakobsen KD, Hansen T, Melle I, Steen VM, Werge T, Andreassen OA. 2008. Association analysis of schizophrenia on 18 candidate genes involved in neuronal migration: MDGA1 as a new susceptibility gene. Am J Med Genet Part B Neuropsychiatr Genet 147B: 10891100.
  • Lievers KJ, Boers GH, Verhoef P, den Heijer M, Kluijtmans LA, van der Put NM, Trijbels FJ, Blom HJ. 2001. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med 79: 522528.
  • Lima CS, Nascimento H, Bonadia LC, Teori MT, Coy CS, Goes JR, Costa FF, Bertuzzo CS. 2007. Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma. Int J Colorectal Dis 22: 757763.
  • Lin JJ, Yueh KC, Liu CS, Liu JT, Lin SZ. 2007. 5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease. Acta Neurol Taiwan 16: 150157.
  • Mager A, Koren-Morag N, Shohat M, Harell D, Battler A. 2005. Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes. Am J Cardiol 95: 14201424.
  • Muntjewerff JW, Kahn RS, Blom HJ, den Heijer M. 2006. Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: A meta-analysis. Mol Psychiatry 11: 143149.
  • Peerbooms O, Rutten BP, Decoster J, van Os J, Kenis G, De Hert M, van Winkel R. 2010. No association between MTHFR C677T or A1298C and age at onset of schizophrenia. Am J Med Genet Part B Neuropsychiatr Genet 153B: 13621363.
  • Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I, Pietilainen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Borglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthoj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jurgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R. 2011. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43: 969976.
  • Saetre P, Vares M, Werge T, Andreassen OA, Arinami T, Ishiguro H, Nanko S, Tan EC, Han DH, Roffman JL, Muntjewerff J-W, Jagodzinski PP, Kempisty B, Hauser J, Vilella E, Betcheva E, Nakamura Y, Regland B, Agartz I, Hall H, Terenius L, Jönsson EG. 2011. Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples. Am J Med Genet B Neuropsychiatr Genet 156: 215224.
  • Shi J, Gershon ES, Liu C. 2008. Genetic associations with schizophrenia: Meta-analyses of 12 candidate genes. Schizophr Res 104: 96107.
  • Spitzer RL, Endicott J. 1977. The schedule for affective disorders and schizophrenia, lifetime version. New York, NY: State Psychiatric Institute.
  • Spitzer RL, Endicott J, Robins E. 1978. Research diagnostic criteria; rationale and reliability. Arch Gen Psychiatry 35: 773782.
  • Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietilainen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lönnqvist J, Paunio T, Borglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Bottcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Rethelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA. Genetic Risk and Outcome in Psychosis (GROUP), Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Lim Yoon J, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I. 2009. Common variants conferring risk of schizophrenia. Nature 460: 744747.
  • van der Put NM, Gabreels F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK, van den Heuvel LP, Blom HJ. 1998. A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects? Am J Hum Genet 62: 10441051.
  • Vares M, Saetre P, Deng H, Cai G, Liu X, Hansen T, Rasmussen HB, Werge T, Melle I, Djurovic S, Andreassen OA, Agartz I, Hall H, Terenius L, Jönsson EG. 2010a. Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia. Am J Med Genet Part B Neuropsychiatr Genet 153B: 610618.
  • Vares M, Saetre P, Jönsson EG. 2010b. No association between MTHFR C677T or A1298C and age at onset of schizophrenia: Comments. Am J Med Genet Part B Neuropsychiatr Genet 153B: 1361.
  • Vehof J, Burger H, Wilffert B, Al Hadithy A, Alizadeh BZ, Snieder H. 2012. Clinical response to antipsychotic drug treatment: Association study of polymorphisms in six candidate genes. Eur Neuropsychopharmacol 22: 625631.
  • Wang KS, Liu X, Zhang Q, Aragam N, Pan Y. 2011. Genome-wide association analysis of age at onset in schizophrenia in a European-American sample. Am J Med Genet Part B Neuropsychiatr Genet 156B: 671680.
  • Wigginton JE, Abecasis GR. 2005. PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 21: 34453447.
  • Williams J, Farmer AE, Ackenheil M, Kaufmann CA, McGuffin P, Malaspina D, Friedman JH, Mors O, Mendlewicz J, Mallet J, Maier W, Körner J, Sharp C, McKeon P, Sorbi S, Macciardi F, Azevedo MH, Bloch M, Aschauer H, Gurling H, Tsuang MT, McMahon F, Bowman ES, Berg K, Wynne D, Kirch D, Maxwell ME, Cloninger CR, Reich T. 1996. A multicentre inter-rater reliability study using the OPCRIT computerized diagnostic system. Psychol Med 26: 775783.
  • World Health Organisation 1992. The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organisation.
  • Yue WH, Wang HF, Sun LD, Tang FL, Liu ZH, Zhang HX, Li WQ, Zhang YL, Zhang Y, Ma CC, Du B, Wang LF, Ren YQ, Yang YF, Hu XF, Wang Y, Deng W, Tan LW, Tan YL, Chen Q, Xu GM, Yang GG, Zuo XB, Yan H, Ruan YY, Lu TL, Han X, Ma XH, Cai LW, Jin C, Zhang HY, Yan J, Mi WF, Yin XY, Ma WB, Liu Q, Kang L, Sun W, Pan CY, Shuang M, Yang FD, Wang CY, Yang JL, Li KQ, Ma X, Li LJ, Yu X, Li QZ, Huang X, Lv LX, Li T, Zhao GP, Huang W, Zhang XJ, Zhang D. 2011. Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet 43: 12281231.