SEARCH

SEARCH BY CITATION

REFERENCES

  • Amieva H, Le Goff M, Millet X, Orgogozo JM, Peres K, Barberger-Gateau P, Jacqmin-Gadda H, Dartigues JF. 2008. Prodromal Alzheimer's disease: Successive emergence of the clinical symptoms. Ann Neurol 64(5):492498.
  • Bennett DA, De Jager PL, Leurgans SE, Schneider JA. 2009. Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles. Neurology 72(17):14951503.
  • Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, Wilson RS. 2006. Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 66(12):18371844.
  • Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS. 2012a. Overview and findings from the religious orders study. Curr Alzheimer Res 9(6):628645.
  • Bennett DA, Schneider JA, Bienias JL, Evans DA, Wilson RS. 2005. Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. Neurology 64(5):834841.
  • Bennett DA, Schneider JA, Buchman AS, Barnes LL, Boyle PA, Wilson RS. 2012b. Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res 9(6):646663.
  • Bertram L, Lill CM, Tanzi RE. 2010. The genetics of Alzheimer disease: Back to the future. Neuron 68(2):270281.
  • Bertram L, Tanzi RE. 2008. Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses. Nat Rev Neurosci 9(10):768778.
  • Blacker D, Lee H, Muzikansky A, Martin EC, Tanzi R, McArdle JJ, Moss M, Albert M. 2007. Neuropsychological measures in normal individuals that predict subsequent cognitive decline. Arch Neurol 64(6):862871.
  • Boyle PA, Buchman AS, Wilson RS, Kelly JF, Bennett DA. 2010. The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons. Neuroepidemiology 34(1):4349.
  • Boyle PA, Wilson RS, Aggarwal NT, Tang Y, Bennett DA. 2006. Mild cognitive impairment: Risk of Alzheimer disease and rate of cognitive decline. Neurology 67(3):441445.
  • Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, et al. 2011. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol 69(3):560569.
  • Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker D. 2007. Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Arch Gen Psychiatry 64(12):14431450.
  • Galvin JE, Powlishta KK, Wilkins K, McKeel DW Jr, Xiong C, Grant E, Storandt M, Morris JC. 2005. Predictors of preclinical Alzheimer disease and dementia: A clinicopathologic study. Arch Neurol 62(5):758765.
  • Gatz M, Reynolds CA, Fratiglioni L, Johansson B, Mortimer JA, Berg S, Fiske A, Pedersen NL. 2006. Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry 63(2):168174.
  • Haan MN, Shemanski L, Jagust WJ, Manolio TA, Kuller L. 1999. The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons. JAMA 282(1):4046.
  • Hall CB, Lipton RB, Sliwinski M, Stewart WF. 2000. A change point model for estimating the onset of cognitive decline in preclinical Alzheimer's disease. Stat Med 19(11–12):15551566.
  • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, et al. 2009. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41(10):10881093.
  • Henderson AS, Easteal S, Jorm AF, Mackinnon AJ, Korten AE, Christensen H, Croft L, Jacomb PA. 1995. Apolipoprotein E allele epsilon 4, dementia, and cognitive decline in a population sample. Lancet 346(8987):13871390.
  • Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, et al. 2006. A common genetic variant is associated with adult and childhood obesity. Science 312(5771):279283.
  • Hixson JE, Vernier DT. 1990. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31(3):545548.
  • Hollingworth P, Harold D, Jones L, Owen MJ, Williams J. 2011a. Alzheimer's disease genetics: Current knowledge and future challenges. Int J Geriatr Psychiatry 26(8):793802.
  • Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, et al. 2011b. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 43(5):429435.
  • Kerner B, North KE, Fallin MD. 2009. Use of longitudinal data in genetic studies in the genome-wide association studies era: Summary of Group 14. Genet Epidemiol 33(Suppl 1):S93S98.
  • Klei L, Luca D, Devlin B, Roeder K. 2008. Pleiotropy and principal components of heritability combine to increase power for association analysis. Genet Epidemiol 32(1):919.
  • Klei L, Pollak EJ, Quaas RL. 1988. Genetic and environmental parameters associated with linearized type appraisal scores. J Dairy Sci 71:27442752.
  • Ku CS, Loy EY, Pawitan Y, Chia KS. 2010. The pursuit of genome-wide association studies: Where are we now? J Hum Genet 55(4):195206.
  • Laird NM, Ware JH. 1982. Random-effects models for longitudinal data. Biometrics 38(4):963974.
  • Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, et al. 2009. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41(10):10941099.
  • Lange C, van Steen K, Andrew T, Lyon H, DeMeo DL, Raby B, Murphy A, Silverman EK, MacGregor A, Weiss ST, et al. 2004. A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol 3:Article 17.
  • Mayeux R, Small SA, Tang M, Tycko B, Stern Y. 2001. Memory performance in healthy elderly without Alzheimer's disease: Effects of time and apolipoprotein-E. Neurobiol Aging 22(4):683689.
  • Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, et al. 2011. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 43(5):436441.
  • Naylor M, Lange C. 2012. C2BAT: A novel method for association between genetic markers and multople phenotypes. Harvard University Biostatistics Working Paper Series.
  • Ott J, Rabinowitz D. 1999. A principal-components approach based on heritability for combining phenotype information. Hum Hered 49(2):106111.
  • Petersen RC, Parisi JE, Dickson DW, Johnson KA, Knopman DS, Boeve BF, Jicha GA, Ivnik RJ, Smith GE, Tangalos EG, et al. 2006. Neuropathologic features of amnestic mild cognitive impairment. Arch Neurol 63(5):665672.
  • Psaty BM, O'Donnell CJ, Gudnason V, Lunetta KL, Folsom AR, Rotter JI, Uitterlinden AG, Harris TB, Witteman JC, Boerwinkle E. 2009. Cohorts for eart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet 2(1):7380.
  • R Development Core Team. 2009. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.
  • Riley KP, Snowdon DA, Saunders AM, Roses AD, Mortimer JA, Nanayakkara N. 2000. Cognitive function and apolipoprotein E in very old adults: Findings from the Nun Study. J Gerontol B Psychol Sci Soc Sci 55(2):S69S75.
  • SAS Institute Inc. 2000. Help and documentation. Version SAS 9.1.3. Cary: SAS Institute Inc.
  • Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, et al. 2010. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 303(18):18321840.
  • Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, Craft S, Leverenz JB, Montine TJ. 2007. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol 62(4):406413.
  • Wilson RS, Leurgans SE, Boyle PA, Bennett DA. 2011. Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment. Arch Neurol 68(3):351356.
  • Wilson RS, Schneider JA, Barnes LL, Beckett LA, Aggarwal NT, Cochran EJ, Berry-Kravis E, Bach J, Fox JH, Evans DA, et al. 2002. The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period. Arch Neurol 59(7):11541160.
  • Yang Q, Wang Y. 2012. Methods for analyzing multivariate phenotypes in genetic association studies. J Probability Stat Article ID 652569.
  • Yu L, Boyle P, Wilson RS, Segawa E, Leurgans S, De Jager PL, Bennett DA. 2012. A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment. Neuroepidemiology 39(2):7383.