Susanne Jungwirth, Karl-Heinz Tragl, Peter Fischer, Peter Riederer, and Edna Grünblatt designed the study and wrote the protocol. Susanne Jungwirth and Peter Fischer contributed substantially to acquisition of subjects and data. Claus-Jürgen Scholz, Susanne Jungwirth, Wichart Ildiko, Heike Weber, Jürgen Deckert, and Edna Grünblatt managed the literature searches and analyses. Claus-Jürgen Scholz undertook the statistical analysis. Claus-Jürgen Scholz, Peter Riederer, Jürgen Deckert, and Edna Grünblatt wrote the first draft of the manuscript. All the authors contributed to and have approved the final manuscript.
Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: A 90-month longitudinal study
Version of Record online: 17 JAN 2014
© 2014 Wiley Periodicals, Inc.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Volume 165, Issue 2, pages 184–191, March 2014
How to Cite
2014. Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: A 90-month longitudinal study. Am J Med Genet Part B. 165B:184–191., , , , , , , , , .
None of the authors has any actual or potential conflict of interest, including any financial, personal or other relationships with other people or organizations within three years of beginning the work submitted that could inappropriately influence, or be perceived to influence, this work.
- Issue online: 6 FEB 2014
- Version of Record online: 17 JAN 2014
- Manuscript Accepted: 20 DEC 2013
- Manuscript Received: 6 MAR 2013
- Ludwig Boltzmann Institute of Aging Research, Vienna, Austria
- Alzheimer Forschung Initiativ (AFI), Germany
- IZKF grant. Grant Number: Z-6
Additional supporting information may be found in the online version of this article at the publisher's web-site.
|ajmgb32220-sm-0001-SupTab-S1.xlsx||20K||Table S1. Prospective Studies of the 5-HTTLPR and MAOA-uVNTR for Association With Alzheimer Disease and/or Depression.|
Table S2. VITA Study Demographics. Affection Status as Well as Dimensional Phenotypes Represent Life-time Summaries of Diagnoses Made in the Four VITA Examinations; Details are Outlined in the Sample Description.
Table S3: Genotype counts of 5HTTLPR and MAOA-uVNTR in Subsets of the VITA Study Cohort, Along With p-values Resulting From Hardy–Weinberg Equilibrium (HWE) Tests.
Table S4: Genetic Effect Model Choice for Analyzed Outcomes.
Table S5. The Current Power to Find Nominal Associations of the Estimated Effect Sizes for the Examined Polymorphisms and Outcomes.
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.