Selective Lactam Formation from Amino Alcohols Using Polymer-Incarcerated Gold and Gold/Cobalt Nanoparticles as Catalysts under Aerobic Oxidative Conditions

Authors

  • Jean-François Soulé,

    1. Dr. J.-F. Soulé, Dr. H. Miyamura, Prof. Dr. S. Kobayashi*, Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan), Fax: (+81) 3-5684-0634
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  • Hiroyuki Miyamura,

    1. Dr. J.-F. Soulé, Dr. H. Miyamura, Prof. Dr. S. Kobayashi*, Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan), Fax: (+81) 3-5684-0634
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  • Prof. Dr. Shū Kobayashi

    Corresponding author
    1. Dr. J.-F. Soulé, Dr. H. Miyamura, Prof. Dr. S. Kobayashi*, Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan), Fax: (+81) 3-5684-0634
    • Dr. J.-F. Soulé, Dr. H. Miyamura, Prof. Dr. S. Kobayashi*, Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan), Fax: (+81) 3-5684-0634
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Abstract

original image

Gold! Lactams were synthesized through a tandem oxidation process from amino alcohols by using polymer-incarcerated gold or gold/cobalt nanoparticles with or without carbon black as catalysts and molecular oxygen as a terminal oxidant. This system offers an environmentally innocuous method for the preparation of lactams with only water as a side product.

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