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Catalyst-free Synthesis of Betti bases in a Mannich-Type Reaction

Authors

  • Prof. Mazaahir Kidwai,

    Corresponding author
    1. Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007 (India), Fax: (+91) 1127666235
    • Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007 (India), Fax: (+91) 1127666235
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  • Ritika Chauhan

    1. Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007 (India), Fax: (+91) 1127666235
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Abstract

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Betti you can: An efficient, sustainable, and a catalyst-free procedure for the synthesis of Betti bases by a one-pot, three-component, Mannich-type condensation of secondary amines, aldehydes, and β-naphthol in polyethylene glycol at room temperature has been developed. The products do not require purification by chromatography and the solvent was remarkably recyclable for up to four runs.

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