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Keywords:

  • primates;
  • 25-hydroxyvitamin D3;
  • 1,25-dihydroxyvitamin D3;
  • receptor;
  • nutrition;
  • Callithrix;
  • Saguinus;
  • Alouatta;
  • Cebus;
  • Cercopithecus;
  • Macaca;
  • Mandrillus;
  • Presbytis;
  • Gorilla;
  • Pongo

Abstract

We measured the serum concentration of 25-hydroxyvitamin D3 (25-OH-D3) and 1,25-dihydroxyvitamin D3 (1,25-[OH]2-D3) in 23 different Platyrrhines from four different genera and in 21 Catarrhines from six different genera in residence at the Los Angeles Zoo. The mean (±S.E.) serum concentration of 1,25-(OH)2-D3 was significantly greater in Platyrrhines (810 ± 119 pg/ml) than in Catarrhines (61 ± 5 pg/ml), suggesting that high circulating concentrations of the active vitamin D hormone were a characteristic of New World primates in both the Cebidae and Callitrichidae family. This increase in the serum concentration of 1,25-(OH)2-D3 is probably an adaptational response on the part of Platyrrhini to offset a relative decrease in the concentration of specific receptor for 1,25-(OH)2-D3 in target tissues for the hormone.