Contract grant sponsor: NIH; contract grant numbers: MH-92923; NS-42867; HD-56232; HD-60563.
Initiation of Joint Attention is Associated with Morphometric Variation in the Anterior Cingulate Cortex of Chimpanzees (Pan troglodytes)
Article first published online: 8 JAN 2013
© 2013 Wiley Periodicals, Inc.
American Journal of Primatology
Special Issue: Special Section on Primate Neuroethology
Volume 75, Issue 5, pages 441–449, May 2013
How to Cite
HOPKINS, W. D. and TAGLIALATELA, J. P. (2013), Initiation of Joint Attention is Associated with Morphometric Variation in the Anterior Cingulate Cortex of Chimpanzees (Pan troglodytes). Am. J. Primatol., 75: 441–449. doi: 10.1002/ajp.22120
- Issue published online: 25 MAR 2013
- Article first published online: 8 JAN 2013
- Manuscript Accepted: 23 NOV 2012
- Manuscript Revised: 14 NOV 2012
- Manuscript Received: 22 MAY 2012
- NIH. Grant Numbers: MH-92923, NS-42867, HD-56232, HD-60563
- anterior cingulate cortex;
- joint attention
In developing human children, joint attention (JA) is an important preverbal skill fundamental to the development of language. Poor JA skills have been described as a behavioral risk factor for some neurodevelopmental disorders, such as autism spectrum disorder. It has been hypothesized that the anterior cingulate cortex (ACC) plays an important role in the development of JA in human children. Here, we tested whether the morphometry and lateralization of the ACC differed between chimpanzees that were classified as either consistently or inconsistently engaging in JA with a human experimenter. Results showed that chimpanzees that performed poorly on the JA task had larger gray matter (GM) volumes in the ACC compared to apes that performed well on the task. In addition, both population-level asymmetries and sex differences in the volume of GM were found within the ACC. Specifically, females had relatively larger GM volumes in two of the three subregions of the ACC compared to males, and significant leftward asymmetries were found for two of the subregions whereas a rightward bias was observed in the third. Based on these findings, we suggest that the ACC plays an important role in mediating JA, not just in humans, but also chimpanzees. We further suggest that the differences found between groups may reflect inherent differences in the amount of white matter within the ACC, thereby suggesting reduced connectivity between the ACC and other cortical regions in chimpanzees with poor JA skills. Am. J. Primatol. 75:441-449, 2013. © 2013 Wiley Periodicals, Inc.