Article

The St. Lawrence Island Eskimos: Genetic variation and genetic distance

  1. Robert E. Ferrell1,
  2. Ranajit Chakraborty1,
  3. Henry Gershowitz2,
  4. W. S. Laughlin3,
  5. W. J. Schull1

Article first published online: 27 APR 2005

DOI: 10.1002/ajpa.1330550309

Issue

American Journal of Physical Anthropology

American Journal of Physical Anthropology

Volume 55, Issue 3, pages 351–358, July 1981

Additional Information

How to Cite

Ferrell, R. E., Chakraborty, R., Gershowitz, H., Laughlin, W. S. and Schull, W. J. (1981), The St. Lawrence Island Eskimos: Genetic variation and genetic distance. Am. J. Phys. Anthropol., 55: 351–358. doi: 10.1002/ajpa.1330550309

Author Information

  1. 1

    Center for Demographic and Population Genetics, Graduate School of Biomedical Sciences, University of Texas Health Science Center, Houston, Texas 77025

  2. 2

    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109

  3. 3

    Laboratory of Biological Anthropology, University of Connecticut, Storrs, Connecticut 06268

Publication History

  1. Issue published online: 27 APR 2005
  2. Article first published online: 27 APR 2005
  3. Manuscript Accepted: 23 JAN 1981
  4. Manuscript Received: 22 SEP 1980

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Keywords:

  • St. Lawrence Island;
  • Eskimos;
  • Genetic distance;
  • Admixture;
  • Genetic polymorphism

Abstract

The Eskimos of St. Lawrence Island have been typed for genetic variation at 44 discrete genetic loci. Three private polymorphisms, at the 2,3-diphosphoglycerate mutase, peptidase B, and purine nucleoside phosphorylase loci, have been observed, which may be useful in future studies of genetic relationships between Eskimos and other circumpolar populations. Genetic distance analysis reveals a close relationship between the St. Lawrence Island Eskimos and other Eskimo populations and that the Eskimo populations form a distinct cluster from Amerindian populations. The St. Lawrence Island Eskimos appear to be more similar to Asiatic Eskimos than to other groups. Caucasian admixture in this population is estimated to be between 2 and 7%.

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