Land, language, and loci: mtDNA in Native Americans and the genetic history of Peru
Article first published online: 6 DEC 2004
Copyright © 2004 Wiley-Liss, Inc.
American Journal of Physical Anthropology
Volume 127, Issue 3, pages 351–360, July 2005
How to Cite
Lewis, C. M., Tito, R. Y., Lizárraga, B. and Stone, A. C. (2005), Land, language, and loci: mtDNA in Native Americans and the genetic history of Peru. Am. J. Phys. Anthropol., 127: 351–360. doi: 10.1002/ajpa.20102
- Issue published online: 2 JUN 2005
- Article first published online: 6 DEC 2004
- Manuscript Accepted: 30 DEC 2003
- Manuscript Received: 4 AUG 2003
- University of New Mexico Research Alocation Grant
- mitochondrial DNA;
- genetic distance;
- American Indian
Despite a long history of complex societies and despite extensive present-day linguistic and ethnic diversity, relatively few populations in Peru have been sampled for population genetic investigations. In order to address questions about the relationships between South American populations and about the extent of correlation between genetic distance, language, and geography in the region, mitochondrial DNA (mtDNA) hypervariable region I sequences and mtDNA haplogroup markers were examined in 33 individuals from the state of Ancash, Peru. These sequences were compared to those from 19 American Indian populations using diversity estimates, AMOVA tests, mismatch distributions, a multidimensional scaling plot, and regressions. The results show correlations between genetics, linguistics, and geographical affinities, with stronger correlations between genetics and language. Additionally, the results suggest a pattern of differential gene flow and drift in western vs. eastern South America, supporting previous mtDNA and Y chromosome investigations. Am J Phys Anthropol, 2004. © 2004 Wiley-Liss, Inc.