Is haplogroup X present in extant South American Indians?

Authors

  • Cláudia L. Dornelles,

    1. Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, 91501-970 Porto Alegre, Rio Grande do Sul, Brazil
    2. Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, 90610-001 Porto Alegre, Rio Grande do Sul, Brazil
    Search for more papers by this author
  • Sandro L. Bonatto,

    1. Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, 90610-001 Porto Alegre, Rio Grande do Sul, Brazil
    Search for more papers by this author
  • Loreta B. De Freitas,

    1. Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, 91501-970 Porto Alegre, Rio Grande do Sul, Brazil
    Search for more papers by this author
  • Francisco M. Salzano

    Corresponding author
    1. Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, 91501-970 Porto Alegre, Rio Grande do Sul, Brazil
    • Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, 91501-970, Porto Alegre, RS, Brazil
    Search for more papers by this author

Abstract

A total of 1,159 mitochondrial DNA samples from two Mongolian, two Siberian, and 25 South Native American populations was surveyed for the presence of the C16278T mutation, frequently found in haplogroup X. Material from 25 carriers of that mutation was then sequenced for the hypervariable segment I (HVS-I) control region, and those that still were not classifiable in classical Amerindian haplogroups were further studied. The tests involved all the control region, as well as the presence of characteristic mutations in seven coding fragments, totalling 5,760 base pairs. The results indicate that haplogroup X is not present in these samples. Am J Phys Anthropol, 2005. © 2004 Wiley-Liss, Inc.

Ancillary