Research Article

Paleogenetical study of pre-Columbian samples from Pampa Grande (Salta, Argentina)

  1. Fransisco R. Carnese1,†,
  2. Fanny Mendisco2,3,†,*,
  3. Christine Keyser3,
  4. Cristina B. Dejean1,
  5. Jean-Michel Dugoujon2,
  6. Claudio M. Bravi4,
  7. Bertrand Ludes3,
  8. Eric Crubézy2

Article first published online: 16 NOV 2009

DOI: 10.1002/ajpa.21165

Issue

American Journal of Physical Anthropology

American Journal of Physical Anthropology

Volume 141, Issue 3, pages 452–462, March 2010

Additional Information

How to Cite

Carnese, F. R., Mendisco, F., Keyser, C., Dejean, C. B., Dugoujon, J.-M., Bravi, C. M., Ludes, B. and Crubézy, E. (2010), Paleogenetical study of pre-Columbian samples from Pampa Grande (Salta, Argentina). American Journal of Physical Anthropology, 141: 452–462. doi: 10.1002/ajpa.21165

Author Information

  1. 1

    Universidad de Buenos Aires, Facultad de Filosofía y Letras, Instituto de Ciencias Antropológicas, Sección Antropología, Biológica, Buenos Aires 1406, Argentina

  2. 2

    Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), CNRS FRE 2960, Toulouse 31000, France

  3. 3

    Laboratoire d'Anthropologie moléculaire EA: 4438, Institut de Médecine Légale, Université de Strasbourg, Strasbourg Cedex 67085, France

  4. 4

    Laboratorio de Genética Molecular Poblacional, Instituto Multidisciplinario de Biología Celular (IMBICE), La Plata 1900, Argentina

  1. †

    The first two authors contributed equally to this work.

*Laboratoire d'Anthropologie moléculaire, Institut de Médecine Légale, 11 rue Humann, Strasbourg Cedex 67085, France

Publication History

  1. Issue published online: 1 FEB 2010
  2. Article first published online: 16 NOV 2009
  3. Manuscript Accepted: 21 JUL 2009
  4. Manuscript Received: 19 APR 2009

Funded by

  • ECOS-/Sud/ (France––Ministère des Affaires Etrangères and Ministère de la Recherche et de l'Enseignement Supérieur)
  • ECOS-SETCIP (Argentina––Secretaría de Ciencia y Técnia de la Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas CONICET)
  • Laboratoire AMIS (Toulouse; France)
  • Institut de Médecine Légale (Strasbourg; France)
  • CNRS (Centre National de la Recherche Scientifique)

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Keywords:

  • ancient DNA;
  • Amerindians;
  • mtDNA;
  • STRs;
  • Y-STR

Abstract

Ancient DNA recovered from 21 individuals excavated from burial sites in the Pampa Grande (PG) region (Salta province) of North-Western Argentina (NWA) was analyzed using various genetic markers (mitochondrial DNA, autosomal STRs, and Y chromosomal STRs). The results were compared to ancient and modern DNA from various populations in the Andean and North Argentinean regions, with the aim of establishing their relationships with PG. The mitochondrial haplogroup frequencies described (11% A, 47% B, and 42% D) presented values comparable to those found for the ancient Andean populations from Peru and San Pedro de Atacama. On the other hand, mitochondrial and Y chromosomal haplotypes were specific to PG, as they did not match any other of the South American populations studied. The described genetic diversity indicates homogeneity in the genetic structure of the ancient Andean populations, which was probably facilitated by the intense exchange network in the Andean zone, in particular among Tiwanaku, San Pedro de Atacama, and NWA. The discovery of haplotypes unique to PG could be due to a loss of genetic diversity caused by recent events affecting the autochthonous populations (establishment of the Inca Empire in the region, colonization by the Europeans). Am J Phys Anthropol 2010. © 2009 Wiley-Liss, Inc.

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